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Updated: Feb 7, 2026

Computed Tomography (CT) Guided Implantation of a Totally Implantable Venous Access Port (TIVAP) through Subclavian Vein
Published on: January 13, 2026
Complications with fully implantable venous access systems in oncologic patients
L Laurenzi1, C Fimiani, N Faglieri
1Intensive Care Unit and Pain Therapy, Regina Elena Cancer Institute, Rome, Italy.
Long-term central venous catheterization in cancer patients can lead to complications like infections and thrombosis. Fully implantable venous access systems offer a useful, cost-effective solution for oncologic care.
Area of Science:
- Oncology
- Vascular Access Devices
- Medical Complications
Background:
- Long-term central venous catheterization is crucial for treating patients with malignant hemopathies and solid tumors.
- Assessing complications associated with these devices is essential for patient safety and treatment efficacy.
Purpose of the Study:
- To evaluate the complications arising from long-term central venous catheterization in patients with malignant hemopathies or solid tumors.
- To determine the incidence and types of complications, including infections and mechanical issues.
Main Methods:
- A retrospective study was conducted from June 1988 to June 1993.
- Data were collected from 211 consecutive patients requiring 223 venous access devices for long-term use.
- Consistent analysis was performed on 161 patients.
Main Results:
- Fourteen catheter systems were removed due to complications.
- Infections were the most frequent complication, with an overall incidence of 9.6% (0.033 per 100 catheter days/patient).
- A significant difference in infection rates was observed between malignant hemopathies (24%) and solid tumors (4.8%) (P = 0.0002). Thrombosis occurred in 3% of cases.
Conclusions:
- Fully implantable venous access systems demonstrate significant utility in oncologic patients.
- The cost-benefit ratio supports the use of these systems for long-term venous access in cancer care.
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