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Treatment of persistent glaucoma secondary to periocular corticosteroids
L Akduman1, A E Kolker, D L Black
1Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO 63110-1096, USA.
Purpose:
To describe two patients with uveitis who developed increased intraocular pressure that was unresponsive to maximum medical therapy eight and 13 months after periocular injection of triamcinolone acetonide.
Methods:
Excised periocular tissue was analyzed for corticosteroid activity by gas chromatography and mass spectrometry.
Results:
Excision of the periocular tissue, which contained visible triamcinolone acetonide, resulted in a normal intraocular pressure within 14 days in both patients. Analysis of the excised tissue disclosed residual corticosteroid in one of the two patients.
Conclusion:
Removal of periocular tissue containing injected corticosteroids may facilitate the management of patients developing increased intraocular pressure unresponsive to maximum medical therapy.