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Published on: August 16, 2021
Physiologic control of cardiac assist devices
A W Hall1, O Soykan, A H Harken
1Brady Research, Medtronic Inc., Fridley, Minnesota 55432, USA.
Total artificial hearts (TAHs) and biventricular assist devices (BVADs) can be improved with a new control algorithm. This system uses patient signals to optimize cardiac output and oxygen delivery, enhancing patient care.
Area of Science:
- Biomedical Engineering
- Cardiovascular Research
- Medical Device Technology
Background:
- Current total artificial hearts (TAHs) and biventricular assist devices (BVADs) primarily rely on single-parameter control, often based on preload, leading to fixed oxygen delivery.
- Existing control mechanisms for TAHs and BVADs aim for physiologic demand response and output balance but do not adequately address variable patient oxygen consumption.
Observation:
- Significant fluctuations in oxygen consumption are normal in patients with TAHs and BVADs.
- Specific patient-generated signals can effectively reflect these physiological variations in oxygen consumption.
Findings:
- A novel multitiered control algorithm is proposed, utilizing multiple patient-generated signals to adapt device output.
- This algorithm aims to provide more responsive and physiologically appropriate cardiac output (CO) compared to current single-parameter systems.
Implications:
- The proposed control system has the potential to improve response times and achieve more physiologic cardiac outputs in TAH and BVAD patients.
- Leveraging existing microprocessor technology, similar to that in modern implantable pulse generators (IPGs), can facilitate the development and implementation of this advanced control strategy.
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