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Isolation and structure of staph-cAM373 produced by Staphylococcus aureus that induces conjugal transfer of
J Nakayama1, S Igarashi, H Nagasawa
1Department of Applied Biological Chemistry, University of Tokyo, Japan.
Bioscience, Biotechnology, and Biochemistry
|June 1, 1996
Abstract:
Enterococus faecalis plasmid pAM373 encodes a mating response to the sex pheromone, cAM373, which is secreted from pAM373-free E. faecalis. cAM373-like activity was detected in a culture filtrate of Staphylococcus aureus. The major active substance, termed staph-cAM373, was isolated, and its structure was identified as a H-Ala-IIe-Phe-IIe-Leu-Ala-Ala-OH heptapeptide.