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[Pharmacology of Catharanthus alkaloids]
1Laboratoire de pharmacocinétique, Institut de Bactériologie, Strasbourg, France.
Bulletin Du Cancer
|March 1, 1996
Abstract:
Catharanthus alkaloids are antitumoral drugs widely used in the treatment of malignant diseases. This review summarizes different aspects of their pharmacology (mechanism of action, resistance, clinical pharmacokinetics) as well as information on their uses in the clinical setting.