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[Role of kinins in local and systemic inflammatory reactions]
1Faculté de Pharmacie de l'Université de Montréal.
Abstract:
The development of highly sensitive and specific immunoassays allowed the characterization of bradykinin and desArg9-BK metabolism in vitro. The same methods were used to study the time course evolution of the tissue content of both kinins in an carragenan inflammatory model. Quantification of T-kininogen in the same animal model allowed to show an influence of BK on the neosynthesis of this acute phase protein.