Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Essential hypertension. Pathophysiological mechanisms and therapy

E D Frohlich

    Archives of Internal Medicine
    |June 1, 1977
    PubMed
    Summary

    Essential hypertension treatment is now tailored to individual physiologic mechanisms. Understanding these mechanisms, as described in Page

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Preventive cardiology: more than just lipid lowering.

    Preventive cardiology·2002
    Same author

    Profiles in cardiology. Harriet P. Dustan.

    Clinical cardiology·2002
    Same author

    Sixtieth anniversary of Angiotensin.

    Hypertension (Dallas, Tex. : 1979)·2001
    Same author

    Apoptosis and glomerular injury after prolonged nitric oxide synthase inhibition in spontaneously hypertensive rats.

    Hypertension (Dallas, Tex. : 1979)·2001
    Same author

    Local hemodynamic changes in hypertension: insights for therapeutic preservation of target organs.

    Hypertension (Dallas, Tex. : 1979)·2001
    Same author

    Isolated systolic hypertension in elderly WKY is reversed with L-arginine and ACE inhibition.

    Hypertension (Dallas, Tex. : 1979)·2001

    Area of Science:

    • Cardiovascular Medicine
    • Pharmacology

    Background:

    • Essential hypertension management requires understanding underlying pathophysiological mechanisms.
    • Page's Mosaic Theory proposed hypertension as a disease of dysregulation.

    Purpose of the Study:

    • To highlight the value of a mechanistic approach in treating essential hypertension.
    • To guide antihypertensive drug selection based on specific physiological drivers.

    Main Methods:

    • Review of existing antihypertensive pharmacotherapy.
    • Application of mechanistic concepts to patient treatment strategies.

    Main Results:

    • A variety of antihypertensive drugs are available for targeted therapy.
    • Mechanistic understanding aids in selecting appropriate treatments.

    Conclusions:

    • Tailoring antihypertensive therapy to specific mechanisms improves patient outcomes.
    • The mechanistic concept of hypertension is crucial for effective clinical management.

    Related Experiment Videos