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Myocardial necrosis and QRS complex changes in the ischemia-reperfusion setting in a baboon model
S Premaratne1, W F LaPenna, B Siu
1Department of Surgery, John A. Burns School of Medicine, Queen's Medical Center, Honolulu, Hawaii, USA.
Background:
This study was performed in attempt to draw a correlation between the percentage of myocardial infarction across the left ventricular wall and changes in the QRS complex in the epicardial ECG in a primate model of ischemia-reperfusion injury.
Methods:
Myocardial infarction was induced in six baboons by ligating the left anterior descending coronary artery for 2h. Using ECG leads, the presence of Q and R waves was recorded along with their associated left ventricular wall thickness.
Results And Conclusions:
The results indicate that Q-wave development and R-wave loss can be correlated with depth of infarct.