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[Preparation and characterization of liposomal adriamycin]
Zhonghua Yi Xue Za Zhi
|October 1, 1995
Abstract:
We established a more suitable methodology for preparing liposomal adriamycin (Lipo-ADM) by a remote loading technique. This procedure is convenient, simple with an entrapment efficiency of 95%. The mean diameter of liposome is about 100nm showing unilamellar spherical shape. The leakage ratio is about 10% within 24hr. Those characteristics fit for clinical demand.