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Familial supernumerary chromosome and malignancy
J M Milunsky1, H E Wyandt, A Milunsky
1Center for Human Genetics, Boston University School of Medicine, Massachusetts 02118, USA.
Cancer Genetics and Cytogenetics
|July 15, 1996
Summary
A rare marker chromosome 15, identified via prenatal diagnosis, was found in three generations of one family. This genetic anomaly was associated with malignancies including glioma, leukemia, and thyroid cancer.
Area of Science:
- Genetics
- Oncology
- Prenatal Diagnosis
Background:
- Familial marker chromosomes linked to malignancy are not well-documented.
- Supernumerary marker chromosomes can arise during cell division.