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Related Experiment Videos

Trichlorfon toxicity in pigs

K J Dobson

    Australian Veterinary Journal
    |March 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Organophosphorus insecticide trichlorfon can cause poisoning in animals when fed at excessive levels for 3-5 days. This can lead to symptoms like inappetence, tremors, ataxia, and death, highlighting risks of overdosage in farm settings.

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    Area of Science:

    • Veterinary Toxicology
    • Animal Health
    • Insecticide Safety

    Background:

    • Field outbreak of suspected animal poisoning linked to feed medicated with organophosphorus insecticide trichlorfon.
    • Trichlorfon is a commonly used insecticide in agricultural settings.

    Purpose of the Study:

    • To investigate the cause of a suspected poisoning outbreak.
    • To determine the toxicological effects of trichlorfon when administered via feed.
    • To identify conditions leading to trichlorfon overdosage and toxicity in farm animals.

    Main Methods:

    • Controlled feeding experiment with trichlorfon.
    • Observation and recording of clinical signs and mortality.

    Main Results:

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  • Toxicity occurred when trichlorfon was fed for 3-5 days at levels exceeding recommended dosages.
  • Observed signs included inappetence, muscle tremor, ataxia, and death.
  • The study confirmed trichlorfon as the causative agent for the observed poisoning.

    • Conclusions:

    • Overdosage of trichlorfon, even for short durations (3-5 days), can lead to significant animal toxicity and mortality.
    • Farm management practices must carefully adhere to recommended dosages to prevent accidental poisoning.
    • Attention is drawn to specific farm conditions that may predispose animals to trichlorfon overdosage.