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Treatment of scleromyxedema with 2-chlorodeoxyadenosine
L S Davis1, S Sanal, O P Sangueza
1Department of Medicine, Medical College of Georgia, Augusta 30904, USA.
Journal of the American Academy of Dermatology
|August 1, 1996
Abstract:
Scleromyxedema is an unusual skin disease that is characterized by a proliferation of fibroblasts and an accumulation of mucin. Despite experience with multiple forms of therapy, no single agent has proved uniformly beneficial in this condition. We describe a patient with scleromyxedema who was treated successfully with 2-chlorodeoxyadenosine (2-CdA), a purine analog used mainly in the treatment of lymphoproliferative disorders.