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Drug fever

D H Johnson1, B A Cunha

  • 1Infectious Disease Division, Winthrop-University Hospital, Mineola, NY, USA.

Infectious Disease Clinics of North America
|March 1, 1996
PubMed
Summary
This summary is machine-generated.

Drug fever, a febrile response to medication without rash, affects about 10% of inpatients. Recognizing drug fever is crucial for timely treatment, preventing prolonged hospital stays and unnecessary medical interventions.

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Area of Science:

  • Internal Medicine
  • Clinical Pharmacology
  • Pharmacovigilance

Background:

  • Drug fever is a significant cause of pyrexia in hospitalized patients.
  • It is characterized by fever without a rash, presenting a diagnostic challenge.
  • Estimated incidence in inpatients is approximately 10%.

Purpose of the Study:

  • To highlight the clinical importance of recognizing drug fever.
  • To emphasize the consequences of misdiagnosis or delayed diagnosis.
  • To advocate for early diagnosis and treatment of drug fever.

Main Methods:

  • This abstract is based on a review of existing literature and clinical knowledge regarding drug fever.
  • Diagnostic criteria and clinical presentations are discussed.

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  • The impact of delayed diagnosis on patient outcomes and healthcare costs is analyzed.

    • Main Results:

    • Drug fever can lead to prolonged hospitalization and unnecessary diagnostic tests or treatments.
    • Failure to identify drug fever can result in continued exposure to the offending drug.
    • Accurate diagnosis facilitates prompt withdrawal of the causative agent.

    Conclusions:

    • Early and accurate diagnosis of drug fever is essential for effective patient management.
    • Recognition of drug fever improves the quality and cost-effectiveness of medical care.
    • Prompt treatment of drug fever prevents iatrogenic complications and reduces healthcare resource utilization.