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Pessoine and spinosine, two catecholic berbines from Annona spinescens
E F Queiroz1, F Roblot, A Cavé
1Laboratoire de Pharmacognosie, U.R.A. 1843 CNRS (BIOCIS), Faculté de Pharmacie. Chatenay-Malabry, France.
Journal of Natural Products
|April 1, 1996
Abstract:
The trunk bark and roots of Annona spinescens have been investigated for their alkaloid content. Two new berbine alkaloids, pessoine (1) and spinosine (2), have been isolated from the bark, and their structures were elucidated by spectroscopic methods. Eight known isoquinoline alkaloids were also obtained. The trypanocidal and antileishmanial activities of these isolated compounds have been investigated.