[Acute renal insufficiency in rats in compensatory renal hypertrophy]

Sodium bichromate and glycerol were administered to compare the course of acute renal failure in uninephrectomized rats and rats with two kidneys. The blood serum levels of creatinine, urea, sodium, potassium and osmotically active agents were found to be rather similar in the rats with one and two rats two days after the administration of nephrotic compounds. The concentration of electrolytes in the renal cortex and papilla of these animal groups. It is concluded that acute renal failure caused by glycerol and bichromate runs virtually similarly both in animals with one and two kidneys. Thus, in emergency, such as acute renal failure, the compensatorily hypertrophied kidney ensures the same elimination of nitrogen metabolic-waste products and maintains the electrolytic composition of the internal environment as in the animals with two working kidneys.