[The phospholipid composition of organs and tissues of rabbit]

The phospholipid compositions of 11 organs and tissues of rabbit (brain, heart, lung, liver, muscles, kidney, spleen, bone marrow, pancreas, adrenula, and blood plasma) were comparatively studied by micro-thin-layer chromatography. Total lipid extracts of liver and brain are the most abundant in phospholipid (61,8% and 56,3%, respectively) and that of bone marrow and spleen are the poorest (1,6% and 7,1%, respectively). All the organs and tissues, except blood plasma, contain phosphatidyl choline, phosphatidyl ethanolamine, phosphatidyl serine, phosphatidylinositol, sphingomyelin and diphosphatidylglicerol; the majority of organs contain phosphatidic acid. Lyso-phosphatidyl-choline was detected in blood plasma, bone marrow, adrenula and liver. Phosphatidylglicerol was found only in the lungs. Brain has the lowest content of phosphatidyl choline (34,3%) and the highest contents of phosphatidyl ethanolamine (36,2%) and phosphatidyl serine (12,6%), whereas the heart is the richest in DPG (about 11%). Diphosphatidyl glycerol is the most abundant in the heart (approximately 11%) and phosphatidyl inositol-- in the adrenula (8,1%). Plasma is found to have a high content of choline-containing lipids; however, phosphatidyl serine and phosphatidic acid are absent altogether. Some of the organs and tissues have a similar phospholipid composition; namely brain and kidney, spleen and bone marrow, adrenula and liver.