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The JAK-STAT pathway: summary of initial studies and recent advances
1Rockefeller University, New York, New York 10021, USA.
Recent Progress in Hormone Research
|January 1, 1996
Abstract:
Polypeptides redirect cells by causing immediate changes in gene transcription. A direct connection between polypeptide receptors on the cell surface and genes in the nucleus has been provided by the recognition of the JAK-STAT pathway. Results leading to our present understanding of this pathway are reviewed.