[Relationship between the muscle and connective tissue components of the heart in rats with experimental myocardial infarct]
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Updated: Aug 2, 2026

Acute Myocardial Infarction in Rats
Published on: February 17, 2011
As soon as the first 24 hours of experimental myocardial infarction in rats the "intact" portions of the left ventricle displayed an increase in volume and mean amount of the elements of the connective tissue stroma of the heart. On the second day of the experiment these indices reached the maximum, and on the 20th day--they were similar to those in the control animals myocardium. On the 3rd day the number of muscle nuclei per standard section area proved to increase; this can be attributed to the amitotic division of the myocyte nuclei, since the number of double nuclei increased at the same periods.
As soon as the first 24 hours of experimental myocardial infarction in rats the "intact" portions of the left ventricle displayed an increase in volume and mean amount of the elements of the connective tissue stroma of the heart. On the second day of the experiment these indices reached the maximum, and on the 20th day--they were similar to those in the control animals myocardium. On the 3rd day the number of muscle nuclei per standard section area proved to increase; this can be attributed to the amitotic division of the myocyte nuclei, since the number of double nuclei increased at the same periods.
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