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Updated: Aug 13, 2026

Programmed Electrical Stimulation in Mice
Published on: May 26, 2010
[Diagnostic electrophysiological studies]
1Abteilung für Kardiologie, Departement Medizin, Universitätsklinik, Bern.
Abstract:
Clinical cardiac electrophysiology has evolved over the last decades as a technique to study arrhythmias. Programmed stimulation is a potent tool in assessing the detailed mechanisms of most brady- and tachyarrhythmias as well as a method to judge the efficacy of antiarrhythmic therapy and to stratify patients at risk for the development of life-threatening sustained ventricular arrhythmias. We give an overview of the physiologic mechanisms responsible for paroxysmal supraventricular tachycardias, pre-excited tachycardias as well as sustained ventricular tachycardia in coronary artery disease. Benefit and limitations in assessing the risk for life-threatening tachyarrhythmias in clinically important situations are briefly discussed.
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