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[Trypanocidal structure- activity relationship in 9-thioalkylacridines]
N Bsiri1, C Johnson, M Kayirere
1GERCTOP, URA CNRS, Faculté de Pharmacie, Marseille.
Annales Pharmaceutiques Francaises
|January 1, 1996
Abstract:
A set of 9-thioalkylacridinones, has been prepared and investigated "in vitro" against T. cruzi. Structure-antiparasitic activity relationships are detailed with a view to identify the major structural parameters for the activity under consideration.