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Updated: Feb 14, 2026

Construction of Homozygous Mutants of Migratory Locust Using CRISPR/Cas9 Technology
Published on: March 16, 2022
Abstract:
The location of the terminal oocytes (T) in the ovary of the desert locust dictates whether the penultimate oocytes (T-1) will enter vitellogenesis -- as long as the T oocytes are retained within the ovarioles, vitellogenesis in T-1 oocytes is prevented. When the T oocytes are ovulated into the oviduct, growth of the T-1 oocytes (new T) resumes. Inhibition of vitellogenesis in T-1 oocytes is not due to low rates of JH biosynthesis since high rates of JH biosynthesis were observed in animals in which T oocytes were retained in the ovarioles.
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