Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ocular neuromyotonia

E Ezra1, D Spalton, M D Sanders

  • 1Medical Eye Unit, St Thomas's Hospital, London.

The British Journal of Ophthalmology
|April 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Different goals, common ground: A global perspective on dairy breeding objectives.

JDS communications·2026
Same author

Ellipsoid Zone Reflectivity: Exploring its Potential as a Novel Non-Invasive Biomarker for Assessing Mitochondrial Function.

Neuro-ophthalmology (Aeolus Press)·2024
Same author

Pattern ERGs suggest a possible retinal contribution to the visual acuity loss in acute optic neuritis.

Documenta ophthalmologica. Advances in ophthalmology·2022
Same author

A short- and long-term follow-up study of intersphincteric NASHA Dx implants for fecal incontinence.

Techniques in coloproctology·2022
Same author

Development of an intrauterine infection model in the postpartum dairy cow.

New Zealand veterinary journal·2021
Same author

Comparing effects of bovine Streptococcus and Escherichia coli mastitis on impaired reproductive performance.

Journal of dairy science·2019
Same journal

Reference map of multimodal vision deficits in intermediate age-related macular degeneration: contrast sensitivity and low-contrast visual acuity.

The British journal of ophthalmology·2026
Same journal

Commentary on 'identifying patients with poor visual outcomes after primary rhegmatogenous retinal detachment surgery using machine learning'.

The British journal of ophthalmology·2026
Same journal

Automated deep learning-based retinoschisis and detachment volume measurement in pathological myopia with posterior scleral contraction.

The British journal of ophthalmology·2026
Same journal

Bacterial keratitis: a global review of current practices, challenges and innovations.

The British journal of ophthalmology·2026
Same journal

Real-world integration of an autonomous artificial intelligence system for diabetic retinopathy screening in an endocrinology outpatient clinic.

The British journal of ophthalmology·2026
Same journal

Maternal smoking during pregnancy: a risk factor for early childhood ophthalmologic conditions.

The British journal of ophthalmology·2026
See all related articles

Ocular neuromyotonia, a rare condition causing eye muscle spasms, was studied in three new cases. Findings suggest extracellular potassium may trigger spasms, and anticonvulsants can be effective treatments.

Area of Science:

  • Neurology
  • Ophthalmology

Background:

  • Ocular neuromyotonia is a rare condition characterized by spontaneous extraocular muscle spasms, with only 14 previous cases reported.
  • This study presents three new cases, two with unique features, to further elucidate the underlying mechanisms.

Observation:

  • Two patients presented with third nerve neuromyotonia, one linked to an internal carotid artery aneurysm and the other to pituitary tumor irradiation.
  • Selective activation of extraocular muscles was observed, triggered by prolonged voluntary activation.
  • A unique case of fourth nerve involvement showed superior oblique muscle spasms induced solely by alcohol consumption.

Findings:

  • Third nerve neuromyotonia cases responded to carbamazepine, with one experiencing improvement in partial nerve paresis.
  • One patient with fourth nerve involvement remained asymptomatic by avoiding alcohol.

Related Experiment Videos

  • Prolonged voluntary muscle action and imaging are crucial for diagnosis and excluding intracranial lesions.

    • Implications:

    • Extracellular potassium concentration is implicated in the spontaneous firing of axons, potentially causing ocular neuromyotonia.
    • Anticonvulsant therapy should be considered for patients diagnosed with ocular neuromyotonia.
    • Early diagnosis and appropriate management, including imaging and medication, are vital for effective treatment.