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Adrenal gland leiomyoma in a child with acquired immunodeficiency syndrome
J A Jimenez-Heffernan1, D Hardisson, J Palacios
1Department of Pathology, Hospital La Paz, Madrid, Spain.
Abstract:
An adrenal gland leiomyoma was incidentally found at autopsy in a 2-year-old boy with acquired immunodeficiency syndrome (AIDS). Smooth muscle neoplasms have been described in pediatric AIDS and affect mainly the tracheobronchopulmonary, gastrointestinal, and hepatobiliary systems. An association between Epstein-Barr virus (EBV) and smooth muscle tumors in patients with AIDS has been described. This case is the first leiomyoma to be reported in the adrenal gland of a child with AIDS. EBV genome was demonstrated in the tumor by polymerase chain reaction.