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Updated: Aug 8, 2026

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
Published on: October 21, 2022
Quantitative measurement of corneal haze after myopic PRK
S S Chang1, D M Maurice, S Ramirez-Florez
1Department of Ophthalmology, Stanford University Medical Center, Calif., USA.
Objective:
To design and evaluate an instrument for the objective measurement of haze in rabbits after myopic PRK.
Methods:
A circular fluorescent lamp bulb projected light onto the cornea through a circular collimating aperture covered with an orange filter. The image was collected on a centrally mounted CCD camera and the profile of the haze circle along its horizontal diameter determined.
Results:
Haze circles were observed and quantitated. In the first weeks, they were donut-shaped, frequently with a central bright area, but later they became square-topped. The instrument reproduced measurements with an error of a few percentage points and showed good long-term stability.

