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Updated: Aug 7, 2026

Photodynamic Therapy with Blended Conducting Polymer/Fullerene Nanoparticle Photosensitizers
Published on: October 28, 2015
[Photodynamic effect of HPD on DNA functions]
Abstract:
After treatment of the DNA by HPD and light the number of transformants of the M13mp8 DNA obviously decreased during the period of transforming the treated DNA into E coli. Meanwhile some of the mutation sequences appeared in the DNA which recovered from the DNA/HPD/Light transformant. It showed that the wrong replication happened because of the mutated template. Also the in vitro run-off transcription of IL-2R alpha gene was affected by HPD and light. It means that the DNA functions are influenced by the photodynamic effects.
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