Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The colposcopic screening

M Hilgarth1, M Menton

  • 1Universitäts-Frauenklinik, Freiburg, Germany.

European Journal of Obstetrics, Gynecology, and Reproductive Biology
|March 1, 1996
PubMed
Summary

Colposcopy is a superior screening tool for cervical dysplasia compared to cytology. It accurately detects HPV-related lesions and corrects false-negative results from Pap smears, improving diagnostic accuracy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative genome analysis, predicted lifestyle and antimicrobial strategies of Lactococcus carnosus and Lactococcus paracarnosus isolated from meat.

Microbiological research·2022
Same author

Proof of concept: predicting the onset of meat spoilage by an integrated oxygen sensor spot in MAP packages.

Letters in applied microbiology·2021
Same author

Diversity and anaerobic growth of Pseudomonas spp. isolated from modified atmosphere packaged minced beef.

Journal of applied microbiology·2019
Same author

An adapted isolation procedure reveals Photobacterium spp. as common spoilers on modified atmosphere packaged meats.

Letters in applied microbiology·2018
Same author

Assertiveness of meat-borne Lactococcus piscium strains and their potential for competitive exclusion of spoilage bacteria in situ and in vitro.

Journal of applied microbiology·2018
Same author

Monitoring of spoilage-associated microbiota on modified atmosphere packaged beef and differentiation of psychrophilic and psychrotrophic strains.

Journal of applied microbiology·2017

Area of Science:

  • Gynecology
  • Oncology
  • Pathology

Background:

  • Cervical intraepithelial neoplasia (CIN) is a precursor to cervical cancer.
  • Cervical cancer screening relies on cytology (Pap smears) and colposcopy.
  • Accurate detection of CIN is crucial for effective management and prevention of cervical cancer.

Purpose of the Study:

  • To evaluate the effectiveness of colposcopy as a screening tool for cervical intraepithelial neoplasia.
  • To compare the diagnostic accuracy of colposcopy with cytology against histological confirmation.
  • To assess colposcopy's role in managing HPV-related cervical lesions.

Main Methods:

  • Retrospective analysis of 392 patients with histologically confirmed intraepithelial neoplasia.
  • Comparison of colposcopic findings and cytologic results with final histologic diagnoses.
  • Evaluation of diagnostic correlation and false-negative rates for both methods.

Main Results:

  • Colposcopy showed significantly higher correlation with histologic diagnosis (84-97%) than cytology.
  • Colposcopy had a lower false-negative rate (5%) for mild dysplasia and condylomatous lesions compared to cytology (39% and 26%).
  • Colposcopy demonstrated superior accuracy in grading high-grade lesions (CIN III: 85% vs. cytology: 61%).

Conclusions:

  • Colposcopy is an excellent tool for detecting HPV-induced cervical lesions, including subclinical ones and CIN I.
  • Colposcopy effectively corrects the high false-negative rate associated with cytology, serving as a quality assurance measure.
  • Colposcopy is a superior screening and grading method for dysplastic cervical lesions compared to cytology.

Related Experiment Videos