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Therapy-related myeloid leukemia
1Section of Hematology/Oncology, Pritzker School of Medicine, University of Chicago, Illinois, USA.
Hematology/Oncology Clinics of North America
|April 1, 1996
Abstract:
One of the most serious possible consequences of cancer therapy is the development of a second cancer, especially leukemia. Several distinct subsets of therapy-related leukemia can be distinguished currently. These include classic therapy-related myeloid leukemia, leukemia that follows treatment with agents that inhibit topoisomerase II, acute lymphoblastic leukemia, and leukemias with 21q22 rearrangements or inv(16) or t(15;17). These types of leukemia are discussed in detail in this article.