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Related Experiment Videos

Principles of pharmacologic intervention

J M Goodson1

  • 1Forsyth Dental Center, Boston, MA, USA.

Journal of Clinical Periodontology
|March 1, 1996
PubMed
Summary

Pharmacologic interventions, particularly intrapocket drug delivery systems, show promise for supportive periodontal care. These methods, combined with calculus removal and chlorhexidine rinses, can lead to long-term periodontal stabilization.

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Area of Science:

  • Dentistry
  • Periodontology
  • Pharmacology

Background:

  • Conventional periodontal maintenance has limited studies on pharmacologic interventions.
  • Pharmacologic therapy is emerging as a supportive measure for periodontal care.
  • Few studies have explored drug delivery systems for periodontal maintenance.

Purpose of the Study:

  • To evaluate the effectiveness of pharmacologic interventions in supportive periodontal care.
  • To identify principles for optimizing long-term periodontal stabilization using adjunctive therapies.
  • To assess the potential of intrapocket drug delivery systems in managing refractory periodontal sites.

Main Methods:

  • Review of existing studies on pharmacologic interventions for periodontal care.
  • Analysis of principles for adjunctive therapy, including calculus removal and site-specific drug delivery.
  • Consideration of chlorhexidine mouth rinses for infection control during healing.

Main Results:

  • Pharmacologic interventions, especially intrapocket systems, show superior clinical response.
  • Adjunctive therapies can achieve up to 2 years of periodontal stabilization.
  • Eradication of oral infection reservoirs is crucial for long-term stabilization.

Conclusions:

  • Pharmacologic interventions, particularly intrapocket drug delivery, are promising for supportive periodontal care.
  • Combining mechanical debridement with pharmacologic approaches enhances long-term effectiveness.
  • Further clinical trials are needed to optimize and validate these therapeutic strategies.

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