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Quinolone resistance in Oligella urethralis-associated chronic ambulatory peritoneal dialysis peritonitis
U B Riley1, G Bignardi, L Goldberg
1Diagnostic Bacteriology Department, St Mary's Hospital, London, UK.
Abstract:
Oligella urethralis is an organism which is normally isolated as a commensal from the genitourinary tract. We describe the first two reported cases of CAPD-associated peritonitis caused by this organism. Both isolates were found to be resistant to ciprofloxacin, while relatively sensitive to a wide range of antimicrobial drugs. These findings indicate that this organism may be an opportunistic pathogen for CAPD patients, and that extensive ciprofloxacin usage provides a selection pressure for emergence of resistance.
Insights
Oligella urethralis, a common genitourinary commensal, caused peritonitis in two continuous ambulatory peritoneal dialysis (CAPD) patients. Isolates showed ciprofloxacin resistance, suggesting opportunistic behavior and resistance selection pressure from antibiotic use.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Nephrology
Background:
- Oligella urethralis is typically a commensal organism found in the genitourinary tract.
- Peritonitis is a serious complication for patients undergoing continuous ambulatory peritoneal dialysis (CAPD).