Toxicological problems associated with the manufacture of triazapentadienes

1, 3, 5-triazapenta-1, 4-dienes are a new group of pesticides which are particularly effective against acarids. This report concerns various toxicological manifestations which occurred amongst the workforce of a small chemical processing plant engaged in the manufacturer of these substances. The toxic effects noted can be divided into three groups: (1) "Skin flushes", similar to those which have been observed amongst workers using dimethyl formamide. (2) Acute keratoconjunctivitis which occurred as a delayed reaction (between 6 and 12 hours after finishing work). (3) Intoxication following inhalation of isopropyl alcohol fumes. This is of special interest as reputable authorities discount this method of absorption as being a serious problem resulting from the use of isopropyl alcohol in an industrial situation.