Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Risk factors for acute myocardial infarction in Indians: a case-control study

P Pais1, J Pogue, H Gerstein

  • 1Department of Medicine, St John's Medical College, Bangalore, India.

Lancet (London, England)
|August 10, 1996
PubMed
Summary

Smoking and abdominal obesity are key risk factors for heart disease in South Asians. Reducing these, along with managing blood glucose and hypertension, can help prevent ischaemic heart disease (IHD).

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of Humour on Pain Perception among Young Healthy Indian Adults Using Cold Pressor Task.

Kathmandu University medical journal (KUMJ)·2024
Same author

Inter-individual Variation in Pain Sensitivity among Healthy Young Indian Adults- a pilot study.

Kathmandu University medical journal (KUMJ)·2023
Same author

Vitamin D supplementation and adverse skeletal and non-skeletal outcomes in individuals at increased cardiovascular risk: Results from the International Polycap Study (TIPS)-3 randomized controlled trial.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2023
Same author

Effects of repeated exposures to experimental cold pain stimulus on pain perception in healthy young Indian men.

Medical journal, Armed Forces India·2022
Same author

Changing the paradigm in postherpetic neuralgia treatment: lidocaine 700 mg medicated plaster.

European review for medical and pharmacological sciences·2022
Same author

Patient and caregiver reported facilitators of self-care among patients with chronic heart failure: report from a formative qualitative study.

Wellcome open research·2020

Area of Science:

  • Cardiology
  • Epidemiology
  • Public Health

Background:

  • South Asians exhibit a higher risk of ischaemic heart disease (IHD), with unclear contributing factors.
  • Existing research primarily focuses on migrants to Western countries, potentially not reflecting the situation for most South Asians in India.
  • This study investigates risk factors for IHD specifically within the South Asian population in Bangalore, India.

Purpose of the Study:

  • To determine the relative importance of various risk factors for ischaemic heart disease (IHD) among South Asians in Bangalore, India.
  • To identify key modifiable and non-modifiable factors contributing to acute myocardial infarction (AMI) in this population.

Main Methods:

  • A prospective, hospital-based case-control study involving 200 patients with first acute myocardial infarction (AMI) and 200 matched controls.

Related Experiment Videos

  • Data collection included diet, smoking habits, alcohol consumption, socioeconomic status, waist-to-hip ratio (WHR), blood glucose levels, serum insulin, oral glucose tolerance tests, and lipid profiles.

    • Main Results:

    • Current smoking (cigarettes or beedis) was the most significant predictor of AMI (OR 3.6), with heavy smokers (≥10/day) showing an OR of 6.7.
    • Hypertension and diabetes mellitus were independent risk factors (OR 2.69 and 2.64, respectively).
    • Elevated fasting blood glucose (OR 1.62 per SD) and abdominal obesity (WHR, OR 2.24 per SD) were strong predictors across all ranges. Higher income and vegetarianism showed a protective effect (OR 0.32 and 0.55, respectively). Lipid profiles were not associated with AMI.

    Conclusions:

    • Smoking cessation is crucial for preventing IHD in Asian Indians.
    • Management of hypertension, reduction of blood glucose levels, and addressing central obesity through lifestyle changes are vital preventive strategies.
    • These findings highlight the importance of targeted public health interventions for cardiovascular disease prevention in South Asian populations.