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Unexplained high activity of aspartate aminotransferase (EC 2.6.1.1): a case report
1Department of Clinical Chemistry, Diagnostic Center SSDZ, Delft, Netherlands.
The Netherlands Journal of Medicine
|June 1, 1996
Abstract:
We report a case of unexplained and persistently elevated ASAT activity in serum. This appeared to be due to a macro-enzyme of ASAT, as was demonstrated by protein-A-Sepharose treatment of the serum sample. Although macro-ASAT seems to be clinically irrelevant, unexplained raised ASAT activity without acknowledgement of its macroenzyme nature may lead to unnecessary diagnostic procedures.