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Melanogenic factors: regulation of gene expression
1Laboratory of Molecular Biology, Institute of Chest Diseases, Prague, Czech Republic.
Abstract:
Melanogenesis is a multistep biochemical process resulting in the formation of melanin in pigment cells in the skin and the eye. Three melanogenic factors, tyrosinase, TRP1, and TRP2 participate in the pathway. Here, the regulation of gene expression of these melanocyte-specific markers is shortly reviewed.