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Pharyngeal hypophysis

G N Fuller1, J G Batsakis

  • 1Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston, USA.

The Annals of Otology, Rhinology, and Laryngology
|August 1, 1996
PubMed
Summary
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The pharyngeal hypophysis, originating from Rathke's pouch, is likely present in all humans despite recent challenges. This structure is one of several embryologic derivatives, including rare tumors and cysts.

Area of Science:

  • Embryology
  • Endocrinology
  • Human Anatomy

Background:

  • The pharyngeal hypophysis is an embryologic remnant of Rathke's pouch and its craniopharyngeal duct.
  • Its presence in all humans has been a long-standing concept, though recently questioned.
  • Investigative evidence largely supports the original premise of its universal existence.

Purpose of the Study:

  • To review the evidence regarding the existence of the pharyngeal hypophysis.
  • To clarify the developmental origins and associated structures derived from Rathke's pouch.

Main Methods:

  • Literature review of embryologic and anatomical studies.
  • Analysis of historical and contemporary research on the pharyngeal hypophysis.

Main Results:

Related Experiment Videos

  • The pharyngeal hypophysis is considered a product of Rathke's pouch.
  • Other derivatives of Rathke's pouch include extracranial pituitary tumors, craniopharyngioma, pharyngeal hypopharyngeal cysts, and cerebrospinal fluid rhinorrhea.

Conclusions:

  • The weight of evidence supports the continued belief in the presence of the pharyngeal hypophysis in all humans.
  • Understanding Rathke's pouch derivatives is crucial for diagnosing related pathologies.