Related Experiment Video

Updated: Sep 3, 2026

Intravenous Endotoxin Challenge in Healthy Humans: An Experimental Platform to Investigate and Modulate Systemic Inflammation
07:48

Intravenous Endotoxin Challenge in Healthy Humans: An Experimental Platform to Investigate and Modulate Systemic Inflammation

Published on: May 16, 2016

[Role of gram-negative bacterial endotoxins in infectious and non-infectious diseases]

V G Likhoded, N D Iushchuk, M Iu Iakovlev

    Arkhiv Patologii
    |March 1, 1996
    PubMed

    More Related Videos

    Endotoxin Activity Assay for the Detection of Whole Blood Endotoxemia in Critically Ill Patients06:28

    Endotoxin Activity Assay for the Detection of Whole Blood Endotoxemia in Critically Ill Patients

    Published on: June 24, 2019

    A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats05:56

    A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats

    Published on: February 20, 2021

    Related Concept Videos

    Receptor-mediated Endocytosis01:48

    Receptor-mediated Endocytosis

    Receptor-mediated endocytosis is a process through which bulk amounts of specific molecules can be imported into a cell after binding to cell surface receptors. The molecules bound to these receptors are taken into the cell through inward folding of the cell surface membrane, which is eventually pinched off into a vesicle within the cell. Structural proteins, such as clathrin, coat the budding vesicle and give it its round form.Clathrin-Mediated Endocytosis of LDLOne well-characterized example...
    Receptor-mediated Endocytosis01:20

    Receptor-mediated Endocytosis

    Receptor-mediated endocytosis is when bulk amounts of specific molecules are imported into a cell after binding to cell surface receptors. The molecules bound to these receptors are taken into the cell through inward folding of the cell surface membrane, which is eventually pinched off into a vesicle within the cell. Structural proteins, such as clathrin, coat the budding vesicle.
    Clathrin-Mediated Endocytosis of LDL
    One well-characterized example of receptor-mediated endocytosis is the...
    Gram-negative Bacterial Protein Secretion Systems01:17

    Gram-negative Bacterial Protein Secretion Systems

    Gram-negative bacteria utilize sophisticated protein secretion systems to transport proteins across their double-membrane envelope into the extracellular environment or host cells. Based on their mechanism of action, these systems are classified into one-step and two-step pathways.One-Step Secretion Systems (Types I, III, IV, and VI)One-step secretion systems bypass the periplasm entirely, forming a continuous channel that spans both the inner and outer membranes:Type I Secretion System (T1SS):...
    Bacterial Toxins01:12

    Bacterial Toxins

    Bacterial toxins are sophisticated virulence factors that enable pathogenic bacteria to interact with, invade, and damage host tissues. These toxins fall broadly into two types: protein exotoxins, which are secreted into the environment and target specific host receptors, and lipopolysaccharide endotoxins, which are structural components of the bacterial outer membrane released primarily during bacterial lysis or membrane shedding. Exotoxins generally act more selectively, binding to cell...
    Determinants of Bacterial Pathogenicity and Virulence01:20

    Determinants of Bacterial Pathogenicity and Virulence

    Pathogenic bacteria employ a variety of strategies to establish infections, including the secretion of extracellular enzymes that act as potent virulence factors. These enzymes facilitate bacterial colonization of host tissues and help evade immune surveillance. By targeting structural components of host tissues and interfering with immune mechanisms, these enzymes play a pivotal role in disease progression.Extracellular Enzymes Facilitating Tissue Invasion: Several bacterial pathogens secrete...
    Bacterial Gastroenteritis01:18

    Bacterial Gastroenteritis

    Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...