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Updated: Aug 12, 2026

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Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis
Published on: March 11, 2017
[The morphological changes in the liver in experimentally induced hypercholesterolemia]
Ts Boshnakova1, A Georgiev, D Strashimirov
1Department of Pathological Anatomy, Higher Medical School, Sofia.
Abstract:
The authors examined the liver of 20 rabbits "Newzeland white" and "Chinchila", undergone atherogenic diet with cholesterol (0.3-0.5 g/kg body weight) for 30 and 60 days. They determined cholesterol, lipids, triglicerides and beta-lipoproteins in the serum. The morphologic study revealed accumulation of cholesterol in the hepatocytes, fibrosis, proliferation of the bile ducts and signs of hepatic cirrhosis.

