Study of methods for the detection of HBsAg and HBsAb in hemoderivatives

For application to the control of hemoderivatives of the methods adopted for the detection of HBsAg and HBsAb in sera or plasma, using radioimmunological kits, it is necessary for the methods to have greater sensitivity and reliability, which can be achieved by employing complementary tests or by modifying certain phases of the normal methods. Particularly in the case of hemoderivatives with a high infectivity risk, application of the normal procedures entails problems of a kind such as to rule out the test altogether or to adversely affect its reliability. The preliminary data obtained with modifications of the methods according to the Abbott AUSRIA II and AUSAB RIA kits are here reported; these data seem to indicate that the reliability of the tests is improved.