Thrombogenicity of arterial catheters and guidewires

Thrombus formation on the surface of a variety of arterial catheters and guidewires has been studies in dogs. Heparin-bonding of catheters and guidewires greatly reduced surface thrombus deposition even in the most thrombogenic material tested, and under the conditions of these experiements heparin-bonding was more effective than systemic heparinization.