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Pharmacologic issues in aging

M S Gleason

    Critical Care Nursing Quarterly
    |August 1, 1996
    PubMed
    Summary
    This summary is machine-generated.

    Older adults are the largest medication consumers due to chronic diseases and disability. Safe medication management in critical care requires understanding how aging and illness impact drug pharmacodynamics and pharmacokinetics.

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    Area of Science:

    • Gerontology
    • Pharmacology
    • Critical Care Nursing

    Background:

    • Older adults are the fastest-growing population segment.
    • This demographic is the primary consumer of medications.
    • Factors contributing include perceived disability and chronic diseases.

    Purpose of the Study:

    • To highlight the complexities of medication management in older adults within critical care settings.
    • To emphasize the importance of understanding pharmacodynamics and pharmacokinetics in this population.
    • To inform nursing strategies for safe drug therapy.

    Main Methods:

    • Review of existing literature on aging, pharmacodynamics, and pharmacokinetics.
    • Analysis of factors complicating drug therapy in older critical care patients.

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  • Discussion of nursing implications for safe medication administration.

    • Main Results:

    • Adverse or unpredictable drug reactions frequently complicate acute illness management in older patients.
    • Aging significantly alters drug pharmacodynamics and pharmacokinetics.
    • Critical illness further modifies these physiological processes.

    Conclusions:

    • Effective nursing management of safe drug therapy in critical care necessitates a thorough understanding of pharmacodynamic and pharmacokinetic principles as they relate to aging and critical illness.
    • Addressing medication complexities in older adults is crucial for improving patient outcomes.
    • Further research into tailored medication strategies for geriatric critical care is warranted.