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Related Experiment Video

Updated: Dec 24, 2025

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
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Progression of myopia

R H Kennedy

    Transactions of the American Ophthalmological Society
    |January 1, 1995
    PubMed
    Summary
    This summary is machine-generated.

    Atropine eye drops significantly reduced myopia progression in children compared to controls. The beneficial effects of atropine therapy for myopia persisted even after treatment cessation.

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    Area of Science:

    • Ophthalmology
    • Public Health
    • Pharmacology

    Context:

    • Myopia is a significant public health concern, increasing the risk of vision-threatening conditions.
    • Animal studies suggest atropine can mitigate ocular elongation and myopia progression.
    • Human data on atropine's efficacy for myopia progression is crucial.

    Purpose:

    • To evaluate the efficacy of atropine therapy in reducing myopia progression in a pediatric population.
    • To compare myopia progression rates between children treated with atropine and a matched control group.

    Summary:

    • A study involving 214 children with myopia treated with atropine and 194 matched controls was conducted.
    • Over a median follow-up of 11.7 years, atropine treatment resulted in significantly less myopia progression (0.05 D/year) compared to controls (0.36 D/year).

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  • Final refractions indicated lower myopia levels in the atropine group (2.79 D) versus the control group (3.78 D) by age 20.

    • Impact:

    • Atropine therapy demonstrates a clear association with decreased myopia progression in humans.
    • The therapeutic benefits of atropine for myopia appear to be sustained even after discontinuation of treatment.
    • Findings support atropine as a viable treatment option for managing myopia progression in children.