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Related Experiment Videos

Varicocele: indications for treatment

F Comhaire1, A Zalata, F Schoonjans

  • 1University Hospital Ghent, Department of Internal Medicine, Belgium.

International Journal of Andrology
|December 1, 1995
PubMed
Summary
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Varicocele embolization improves semen quality in infertile men. Early treatment during adolescence is recommended to preserve testicular function and prevent fertility issues.

Area of Science:

  • Urology
  • Reproductive Medicine
  • Andrology

Background:

  • Varicocele affects approximately one-third of men experiencing subfertile semen quality.
  • Subfertility is a common concern among men, with varicocele being a significant contributing factor.

Purpose of the Study:

  • To evaluate the efficacy of transcatheter embolization using Histoacryl for varicocele treatment.
  • To identify factors influencing pregnancy outcomes after varicocele treatment.

Main Methods:

  • Transcatheter embolization utilizing the tissue adhesive Histoacryl was employed for varicocele treatment.
  • Semen quality parameters, including sperm concentration, morphology, and velocity, were assessed post-treatment.

Main Results:

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  • Embolization improved Sertoli cell function, evidenced by increased seminal transferrin concentrations.
  • Significant improvements were observed in sperm concentration, normal morphology, and linear velocity.
  • Pregnancy failure was linked to normal pre-treatment sperm quality, azoospermia with elevated FSH or obstruction, or severe concurrent pathologies.

    • Conclusions:

    • Transcatheter embolization with Histoacryl is an effective treatment for varicocele, enhancing semen parameters.
    • Early detection and treatment of varicocele during puberty or adolescence are crucial for preserving testicular function.
    • Inadequate techniques may explain poor outcomes in some varicocele treatment studies.