Biochemical and histopathological effects of glyphosate on carp, Cyprinus carpio L

Glyphosate, also known by the trade names Roundup and Rodeo for agricultural use, is a broad-spectrum, translocated herbicide, used primarily in agricultural applications, and for vegetation control in non-crop areas. It is used as non-selective herbicide and for aquatic weed control in fish-ponds, lakes, canals, slow running water, etc. (USDA 1984). Glyphosate is perhaps the most important herbicide ever developed. Literature of toxicological and ecotoxicological properties of glyphosate is extremely sparse, considering its importance as herbicide. Generally, glyphosate is slightly toxic to mammals and fish, but it may have an impact on the aquatic environment and also on the other aquatic organisms (USDA 1984). Due to this, its toxicity investigation is very important. The study of sublethal effects is of special importance for toxicological evaluation of compound. The objective of this study was to investigate acute and subacute toxic effects of sublethal glyphosate concentrations in water to carp (Cyprinus carpio L.), one of the commercially most important fish species populating freshwaters of Yugoslavia.