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Fatal cerebellar haemorrhage due to phenprocoumon poisoning
T Höhler1, J Becker, K H Meyer zum Büschenfelde
1Department of Internal Medicine, Johannes Gutenberg-University, Mainz, Germany.
International Journal of Legal Medicine
|January 1, 1996
Abstract:
A 32-year-old patient died of a cerebellar haemorrhage and the blood coagulation analysis before death suggested defective synthesis of vitamin K-dependent clotting factors due to vitamin K deficiency. The post-mortem toxicological examination of different tissues revealed phenprocoumon poisoning as the cause of death. The differential diagnosis of vitamin K deficiency and the toxicology of hydroxycoumarins are discussed.