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Hemodynamic changes associated with strangulation obstruction in cats
J Fevang1, B T Fevang, H Gislason
1Department of Surgery, University of Bergen, Norway.
International Journal of Microcirculation, Clinical and Experimental
|November 1, 1995
Summary
Strangulation obstruction increases venous pressure in the closed loop, impacting intestinal blood flow. Blood flow is primarily determined by arterial pressure and is closely linked to arteriovenous perfusion pressure.
Area of Science:
- Gastroenterology
- Surgical Research
- Physiology
Background:
- Intestinal obstruction is a common surgical emergency.
- Simple intestinal obstruction blood flow is well-studied.
- Blood flow changes in strangulation obstruction remain unclear.
Purpose of the Study:
- To investigate intestinal blood flow changes during strangulation obstruction.
- To determine the relationship between venous pressure and blood flow in strangulation.
- To analyze vascular resistance alterations in obstructed bowel loops.
Main Methods:
- Closed loop strangulation model created in anesthetized cats.
- Intestinal blood flow measured using transit time flowmetry.
- Arterial and venous blood pressures monitored; gasket pressure increased stepwise.
Main Results:
- Increased gasket pressure led to elevated venous pressure in the closed loop.
- Intestinal blood flow decreased with rising venous pressure.
- Blood flow was significantly related to arteriovenous perfusion pressure and arterial pressure.
Conclusions:
- Strangulation obstruction elevates venous pressure within the affected bowel loop.
- Elevated venous pressure plays a role in maintaining intestinal blood flow during obstruction.
- Vascular resistance increases exponentially with venous pressure, particularly at low flow states.