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Synthesis and antimicrobial activity of benzo[a]dihydrocarbazole and benzotetrahydrocyclohept[1,2-b]indole
M Macchia1, C Manera, S Nencetti
1Dipartimento di Scienze Farmaceutiche, Università di Pisa, Italy.
Farmaco (Societa Chimica Italiana : 1989)
|January 1, 1996
Abstract:
A certain number of benzodihydrocarbazoles and benzotetrahydrocycloheptindoles were synthesized and tested for their antimicrobial activity. Compounds substituted on the nitrogen of the tetracyclic systems with a dimethylaminopropyl chain showed an antibacterial activity directed almost exclusively towards Gram-positive bacteria, while their N-unsubstituted analogs were completely inactive.