[Cerebrovascular accident in young adults. A study of 52 cases]
P Martínez-Avilés1, R Barba, C Andújar
1Servicio de Medicina Interna, Hospital Severo Ochoa.
Insights
Despite extensive investigation, 30% of strokes in young adults remain without a clear cause. Early detection of cardiac emboli and managing risk factors can reduce ischemic stroke incidence.
Area of Science:
- Neurology
- Cardiology
- Vascular Medicine
Context:
- Cerebrovascular accidents (CVAs) in individuals under 45 are uncommon but can have significant consequences.
- Understanding the diverse etiologies of stroke in younger populations is crucial for effective management and prevention.
- This study examines CVAs in patients under 45 admitted to Hospital Severo Ochoa over a six-year period.
Purpose:
- To investigate the causes and outcomes of ischemic and hemorrhagic cerebral vascular accidents (CVAs) in patients under 45 years of age.
- To determine the etiological factors contributing to stroke in a young demographic.
- To identify potential risk factors and preventive strategies for stroke in young adults.
Summary:
- A retrospective analysis of 52 cases (23 women, 29 men) of CVA in patients under 45.
- Identified etiologies included cardiac (25%), atherosclerosis (15%), hematological (11%), non-atherosclerotic (15%), migraine (2%), hypertensive (3%), and unknown (29%).
- Atherosclerosis was more prevalent in men, associated with increased cardiovascular risk factors and older age.
Impact:
- Approximately 30% of CVAs in young individuals remain without an etiological diagnosis despite thorough investigation.
- Ischemic CVAs in this age group generally show good neurological recovery and low mortality.
- Proactive detection of cardiac embolic sources, anticoagulation, and cardiovascular risk factor modification may significantly decrease the incidence of ischemic stroke in young adults.
Objective:
A retrospective study of ischaemic and haemorrhagic cerebral vascular accidents in patients under 45 years of age, admitted to hospital Severo Ochoa (Area sanitaria 9 de la Comunidad de Madrid) during a 6 year period.
Method:
23 CVAs in women and 29 in men were studied. The aetiology of each episode was determined following preestablished criteria.
Results:
Aetiology: cardiac 13 (25%), atherosclerosis: 8 (15%), haematological: 6 (11%), non-atherosclerotic: 8 (15%), migraine: 1 (2%), hypertensive: 2 (3%), unknown: 15 (29%). There was a predominance of men in the patients with atherosclerosis. These also had more cardiovascular risk factors and were older than the other patients. All patients with CVA due to antiphospholipid antibodies had multiple CVAs. Examinations used to establish the aetiology were: echocardiogram, angiography, carotid doppler, hypercoagulability studies and the clinical history.
Conclusions:
In spite of extensive study, 30% of the CVAs in young people still have no aetiological diagnosis. In general in ischaemic CVAs, there is good recovery of the neurological defects and a low mortality. The detection and oral anticoagulation of patients with a source of cardiac emboli, and the elimination of cardiovascular risk factors would probably considerably reduce the incidence of ischaemic stroke in young adults.
Related Concept Videos
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Ischemic Stroke l: Introduction
Hemorrhagic Stroke l: Introduction
Hemorrhagic Stroke ll: Pathophysiology
Increased Intracranial Pressure ll: Pathophysiology
Cerebral Edema ll: Pathophysiology


