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Gabapentin adjunctive therapy in neuropathic pain states
H Rosner1, L Rubin, A Kestenbaum
1Department of Anesthesiology, New York Hospital, Cornell Medical Center, New York 10021, USA.
Objective:
This is a report of a trial of the new antiepileptic agent gabapentin in patients with intractable neuropathic pain.
Design:
A case series of patients with a diagnosis of neuropathic pain whose previous management was inadequate were given oral gabapentin in increasing doses and were followed for a minimum of 2 months, monitored for efficacy and side effects.
Setting:
An outpatient pain management center located within a major university medical center.
Patients:
Convenience sample of patients referred for management of intractable neuropathic pain.
Interventions:
Simplification of existing pharmacologic management, addition of gabapentin, and attempted reduction of opiate analgesic doses.
Main Outcome Measures:
Patient self-reports and pain scores in successive office visits.
Results:
Gabapentin provides analgesic activity for patients with neuropathic pain and has the advantage of a low side effect profile and drug toxicity.