Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Quo vadis? Fetal tissue transplantation

M Michejda1

  • 1Georgetown University Medical Center, Washington, DC 20007, USA.

Journal of Hematotherapy
|April 1, 1996
PubMed
Summary

This study reviews fetal tissue transplantation, focusing on second-trimester bone marrow. Intrauterine transplantation in baboons shows potential for future therapeutic applications and tissue banking.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Source of cell injected is a critical factors for short and long engraftment in xeno-transplantation.

Cell proliferation·2008
Same author

Analysis and characterization of hematopoietic progenitor cells from fetal bone marrow, adult bone marrow, peripheral blood, and cord blood.

Pediatric research·1999
Same author

Evaluation of early second trimester maternal serum creatine kinase isoenzyme BB as a marker of poor pregnancy outcome.

Fetal diagnosis and therapy·1998
Same author

Comparative study of hemopoietic precursors from fetal and adult bone marrow: utilization of stem cells derived from miscarriages.

Fetal diagnosis and therapy·1996
Same author

Suitability of fetal tissue for transplantation.

JAMA·1995
Same author

Fetal therapy 1994.

Fetal diagnosis and therapy·1994

Area of Science:

  • Immunology
  • Regenerative Medicine
  • Obstetrics and Gynecology

Background:

  • Fetal tissues possess unique biologic characteristics.
  • Elective and spontaneous abortions provide sources for fetal tissue research.
  • Allogeneic fetal tissue transplantation is a developing field.

Purpose of the Study:

  • To review the epidemiology and biologic characteristics of fetal tissue.
  • To discuss the use of fetal bone marrow from second-trimester abortions.
  • To present data on intrauterine transplantation of human fetal bone marrow into baboon fetuses.

Main Methods:

  • Review of existing literature on fetal tissue harvesting and transplantation.
  • Analysis of data from intrauterine transplantation experiments.
  • Evaluation of fetal bone marrow viability, clonogenic efficiency, and engraftment.

Main Results:

  • Human fetal bone marrow can be successfully transplanted intrauterine into baboon fetuses.
  • The transplanted tissue demonstrates viability and engraftment potential.
  • The study discusses future applications and banking of fetal tissues.

Conclusions:

  • Intrauterine transplantation of human fetal bone marrow is feasible in a primate model.
  • Fetal bone marrow holds promise for future therapeutic strategies.
  • Considerations for tissue banking and long-term use are essential.

Related Experiment Videos