Related Experiment Videos
Differentiation of subsets of CD4+ and CD8+ T cells
T R Mosmann1, S Sad, L Krishnan
1Department of Immunology, University of Alberta, Edmonton, Canada.
Ciba Foundation Symposium
|January 1, 1995
Abstract:
Our knowledge of the cytokine secretion patterns of T cells and other cells is clearly becoming more complex. The T helper 1 (Th1) and Th2 patterns may represent the extremes of a spectrum of cytokine regulatory patterns controlled by several cell types. CD8+ T cells can also secrete either Th1-like or Th2-like cytokine patterns, and they can contribute to bystander B cell activation. Interactions occur between immune cytokine regulatory networks and other systems, and pregnancy and responses against infection can profoundly influence each other.