Can cysteine direct tyrosine in signal transduction for environment-oriented gene control?

Signals are transduced from the cell surface to the nucleus through phosphorylation and dephosphorylation chain reactions of cellular proteins at tyrosine and serine/threonine. Recent evidence suggests that the signal generated through the protein modification at cysteine by oxidation/reduction crosstalks to the protein phosphorylation/dephosphorylation-linked one. I propose that the cysteine-oriented signal potentially directs the tyrosine-oriented one and this mechanism underlies the environment-oriented control of internal signaling for gene expression.